In this brief we identify training gaps existing among healthcare professionals and recommend interventions to address these gaps, specifically among nurses. The HSRC/UKZN study on healthcare professionals (HCPs) conducted in April- May 2020 revealed that nurses felt most ill-prepared compared to medical doctors, specifically in declaring patients as recovered, diagnostic tests, case definitions and treatment guidelines.2 Our data show that nurses were the least confident in the training received for these specific areas.